نوع مقاله : مقاله مروری
نویسندگان
1 زاهدان، دانشگاه سیستان و بلوچستان، دانشکده علوم پایه، گروه شیمی
2 گروه شیمی، دانشکده علوم پایه، دانشگاه سیستان و بلوچستان، زاهدان ، ایران
چکیده
کلیدواژهها
موضوعات
عنوان مقاله [English]
نویسندگان [English]
Epilepsy is one of the most common neurological diseases characterized by random seizures that can lead to other health problems. For patients who need emergency treatment, this has many cognitive, psychological and neurological effects. This disease requires long-term treatment and can limit a person's activities. Epilepsy can cause cognitive impairment or worsen existing disabilities. Several factors, including neuropsychology, seizure type, seizure onset age, and psychosocial issues are involved in these injuries. Discovery of drug toxicity is essential for different categories of drugs, including cardiovascular drugs, antibiotics, anticonvulsants, and anticancer drugs. Administering normal therapeutic doses of antiepileptic drugs in the body can lead to inappropriate levels of this drug in human blood. There is a significant relationship between the concentration of the drug in the blood and its effectiveness, and knowing this relationship is very useful in providing treatment strategies. Therefore, it seems necessary to measure the amount of these drugs in biological samples such as human blood serum and body fluids, industrial wastewater, environmental samples and water in order to control and trace them. Today, by nanotechnology, very small amounts of drugs can be measured in different samples. Thus, the paper examines the use of nanotechnology to preparation of suitable adsorbents for the separation of antiepileptic drugs such as benzodiazepine, valproic acid, phenytoin, oxcarbazepine. , carbamazepine and lamotrigine using chromatographic techniques as well as detection of the drugs in real samples.
کلیدواژهها [English]
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